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Vacuum freeze-drying machine is composed of drying box,refrigeration system vacuum system media heat exchange circulation system,automatic control system,pneumatic system and in-situ cleaning and disinfection system,The quality requirements of freeze-dried products are constant biological activity,uniform appearance and color,full shape, firm structure,fast dissolution,low residual moisture.To obtain high quality products

                     Advantages and disadvantages of freeze-drying machine editing
advantages
Drying method is varied,such as drying,cooking,drying,vacuum drying and spray drying,but ordinary drying methods are generally above 0 ℃ or under higher temperature. Drying products generally have the problem of shrinking volume and hardening texture,most volatile components will be lost,some heat sensitive substances denaturation,inactivation,and some substances even oxidation.Therefore, the dried product compared with before drying,in the character has the very big difference. Freeze-dried law basically under 0 ℃,namely,under the product freeze state parsing is generally not more than 60 ℃ when dry.Under vacuum conditions,when water vapor sublimates directly,the drug remains in the ice shelf when it freezes,forming a spongy porous structure that is nearly constant in size when it dries.If water for injection is added before reuse,it will dissolve immediately.

          Many heat-sensitive substances do not degenerate or become inactivated.

1.dried at low temperature,the loss of some volatile components in the substance is very small.
2.during lyophilization,microbial growth and enzyme action cannot be carried out,so the original character can be maintained.
3.because it is dried in a frozen state,the volume is almost constant,maintaining the original structure and no condensation occurs.
4.as the water in the material exists in the form of ice crystals after pre-freezing,the inorganic  salts dissolved in water  are distributed evenly in the material.During sublimation,dissolved  substances in water are precipitated out,which  avoids the phenomenon of surface hardening caused by the inorganic salts carried by the transfer of moisture from    inside materials to the  surface in common drying methods.

5.after drying,the material is loose and porous,like a sponge.After adding water,it dissolves  quickly and completely , almost immediately returning to its original character.
6.because drying takes place in a vacuum,oxygen is scarce,so some easily oxidized substances are protected.
7.drying can remove more than 95% ~ 99% of the water,so that the product can be preserved  for a long time after drying without deterioration.
8.because the material is in the frozen state,the temperature is very low,so the heat source temperature requirements for heating is not high,the use of room temperature or temperature is not high heater can meet the requirements.If the refrigerating chamber and drying chamber are separated,the drying chamber does not need adiabatic,there will not be a lot of heat loss,so the use of heat energy is very economical.

Product parameters